MTHFR and Other SNPs That Can Affect Health


We interviewed Kendra Becker-Mussante (the “genetic genius”) about MTHFR and other SNPs (genetic mutations) that can affect health.

With the mapping of the human genome in recent years, a lot of research has gone into understanding how some genetic differences called SNPs (Single Nucleotide Polymorphisms) play a role in the etiology of disease and chronic health conditions.

In This Webinar

Dr. Kendra Becker-Mussante joined us to educate us about some of the more commonly known mutations that can affect kids with autism, ADHD, SPD, autoimmune disorders, allergies and asthma. Some of the SNPs we discussed are:

  • CBS
  • SUOX
  • COMT
  • GAD65

Dr. Becker discussed how “genetics loads the gun, but environment pulls the trigger“, meaning that just because you or your child has one or more of these mutations does not necessarily mean that a disease or chronic health condition will occur. Instead, Dr. Becker revealed how diet and lifestyle interventions can affect the expression of these genes and improve health outcomes.

Please note that you will be asked to enter your email address at the 30-minute mark to finish viewing the video.

About Kendra Becker-Mussante MS ND FNP BC APRN

Kendra Becker ND APRNKendra Becker-Mussante MS, ND, FNP, BC, APRN is an integrated physician practicing for over 10 years in Waterford, CT; she is known as the “Genetic Genius”. Her specialties include MTHFR, fertility and treatment of “the 4As” (asthma, autism, allergies, atopy/eczema).

She is an adjunct faculty member at two prominent universities, where she teaches concussion education to physicians and precepts student doctors and nurse practitioners.

Dr. Becker lectures all over the country on topics such as autism, the immune system, MTHFR & genetic mutations that have health implications and “Keeping Healing in the Home”.

She is the author of A Delicious Way to Heal the Gut and All you CAN Eat and was chosen as one of Connecticut’s Top Naturopathic Doctors and 10 Best APRNs. You can find out more about her at her websites and


This webinar is not a substitute for medical advice, treatment, diagnosis, or consultation with a medical professional. It is intended for general informational purposes only and should not be relied on to make determinations related to treatment of a medical condition. Epidemic Answers has not verified and does not guaranty the accuracy of the information provided in this webinar.

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Sources & References

Arnold, P.A., et al. Glutamate transporter gene SLC1A1 associated with obsessive-compulsive disorder. Arch Gen Psychiatry. 2006 Jul;63(7):769-76.

Bidwell, L.C., et al. Genetic influences on ADHD symptom dimensions: Examination of a priori candidates, gene-based tests, genome-wide variation, and SNP heritability. Am J Med Genet B Neuropsychiatr Genet. 2017 Jun;174(4):458-466.

Bowers, K., et al. Glutathione pathway gene variation and risk of autism spectrum disorders. J Neurodev Disord. 2011 Jun;3(2):132-43.

Esmaiel, N.N., et al. The potential impact of COMT gene variants on dopamine regulation and phenotypic traits of ASD patients. Behav Brain Res. 2020 Jan 27;378:112272.

Hausman-Cohen, S., et al. Utilizing Genomically Targeted Molecular Data to Improve Patient-Specific Outcomes in Autism Spectrum Disorder. Int J Mol Sci. 2022 Feb 16;23(4):2167.

Hausman-Cohen, S.R., et al. Genomics of Detoxification: How Genomics can be Used for Targeting Potential Intervention and Prevention Strategies Including Nutrition for Environmentally Acquired Illness. J Am Coll Nutr. 2020 Feb;39(2):94-102.

Hwang, I.W., et al. Association of Monoamine Oxidase A (MAOA) Gene uVNTR and rs6323 Polymorphisms with Attention Deficit and Hyperactivity Disorder in Korean Children. Medicina (Kaunas). 2018 May 18;54(3):32.

Li, Y., et al. Association between MTHFR C677T/A1298C and susceptibility to autism spectrum disorders: a meta-analysis. BMC Pediatrics. 2020(20)449.

Meng, X., et al. Association between MTHFR (677C>T and 1298A>C) polymorphisms and psychiatric disorder: A meta-analysis. PLoS One. 2022 Jul 14;17(7):e0271170.

Rahbar, M.H., et al. Detoxification Role of Metabolic Glutathione S-Transferase (GST) Genes in Blood Lead Concentrations of Jamaican Children with and without Autism Spectrum Disorder. Genes (Basel). 2022 May 29;13(6):975.

Sadeghiyeh. T., et al. Association of MTHFR 677C > T and 1298A > C polymorphisms with susceptibility to attention deficit and hyperactivity disorder. Fetal Pediatr Pathol. 2020 Oct;39(5):422-429.

Way, H., et al. Genomics as a Clinical Decision Support Tool: Successful Proof of Concept for Improved ASD Outcomes. J Pers Med. 2021 Jun 24;11(7):596.

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