ADHD/ADD

Akinbami LJ, Liu X, Pastor PN, Reuben CA. Attention deficit hyperactivity disorder among children aged 5-17 years in the United States, 1998-2009. NCHS Data Brief. 2011(70):1-8. 

Archer T, Kostrzewa RM. Physical exercise alleviates ADHD symptoms: regional deficits and development trajectory. Neurotox Res. 2012;21(2):195-209

Bernfort L, Nordfeldt S, Persson J. ADHD from a socio-economic perspective. Acta Paediatr. 2008;97(2):239-45

Ceylan MF, Sener S, Bayraktar AC, Kavutcu M. Changes in oxidative stress and cellular immunity serum markers in attention-deficit/hyperactivity disorder. Psychiatry Clin Neurosci. 2012;66(3):220-6

Cortese S, Angriman M. Attention-deficit/hyperactivity disorder, iron deficiency, and obesity: is there a link? Postgrad Med. 2014;126(4):155-70.      

Darling, A.L., et al. “Association between maternal vitamin D status in pregnancy and neurodevelopmental outcomes in childhood: results from the Avon Longitudinal Study of Parents and Children (ALSPAC).Br J Nutr 2017 Jun;117(12):1682-1692.

Erskine HE, Ferrari AJ, Polanczyk GV, Moffitt TE, Murray CJ, Vos T, et al. The global burden of conduct disorder and attention-deficit/hyperactivity disorder in 2010. J Child Psychol Psychiatry. 2014;55(4):328-36

Fletcher J, National Bureau of Economic Research. The effects of childhood ADHD on adult labor market outcomes. Cambridge, MA: National Bureau of Economic Research; 2013. 25 p.

Hodgkins P, Montejano L, Sasane R, Huse D. Risk of injury associated with attentiondeficit/ hyperactivity disorder in adults enrolled in employer-sponsored health plans: a retrospective analysis. Prim Care Companion CNS Disord. 2011;13(2)

Kawatani M, Tsukahara H, Mayumi M. Evaluation of oxidative stress status in children with pervasive developmental disorder and attention deficit hyperactivity disorder using urinaryspecific biomarkers. Redox Rep. 2011;16(1):45-6

Mahmoud MM, El-Mazary AA, Maher RM, Saber MM. Zinc, ferritin, magnesium and copper in a group of Egyptian children with attention deficit hyperactivity disorder. Ital J Pediatr. 2011;37:60

Mossin, M.H., et al. “Inverse associations between cord vitamin D and attention deficit hyperactivity disorder symptoms: A child cohort study.Aust N Z J Psychiatry. 2017 Jul;51(7):703-710.

Sabuncuoglu, O. Understanding the relationships between breastfeeding, malocclusion, ADHD, sleep-disordered breathing and traumatic dental injuries. Med Hypotheses. 2013;80(3):315-20

Scassellati C, Bonvicini C, Faraone SV, Gennarelli M. Biomarkers and attention deficit/hyperactivity disorder: a systematic review and meta-analyses. J Am Acad Child Adolesc Psychiatry. 2012;51(10):1003-19 e20

Telford C, Green C, Logan S, Langley K, Thapar A, Ford T. Estimating the costs of ongoing care for adolescents with attention-deficit hyperactivity disorder. Soc Psychiatry Psychiatr Epidemiol. 2013;48(2):337-44

Verlaet AA, Noriega DB, Hermans N, Savelkoul HF. Nutrition, immunological mechanisms and dietary immunomodulation in ADHD. Eur Child Adolesc Psychiatry. 2014;23(7):519-29

Weiss MD, Gadow K, Wasdell MB. Effectiveness outcomes in attention-deficit/hyperactivity disorder. J Clin Psychiatry. 2006;67 Suppl 8:38-45

Books:

Bock, Kenneth. Healing the New Childhood Epidemics: Autism, ADHD, Asthma, and Allergies: The Groundbreaking Program for the 4-A Disorders. New York, NY. Ballantine Books, 2008.

Brandes, Bonnie. The Symphony of Reflexes: Interventions for Human Development, Autism, ADHD, CP, and Other Neurological Disorders, 2016.

Campbell-McBride, Natasha. Gut and Psychology Syndrome: Natural Treatment for Autism, Dyspraxia, A.D.D., Dyslexia, A.D.H.D., Depression, Schizophrenia, 2010.

Crook, William. Help for the Hyperactive Child: A Practical Guide Offering Parents of ADHD Children Alternatives to Ritalin. Square One, 2007

Giustra-Kozek Jennifer. Healing without hurting: treating ADHD, apraxia, and autism spectrum disorders naturally and effectively without harmful medication. Howard Beach, NY: Changing Lives Press, 2014.

Guyol G. Who’s crazy here?: Steps for recovery without drugs for: ADD/ADHD, addiction & eating disorders, anxiety & PTSD, depression, bipolar disorder, schizophrenia, autism. 1st U.S. ed. Stonington, CT: Ajoite Pub., 2010.

Allergies

Bunyavanich S, Rifas-Shiman SL, Platts-Mills TA, Workman L, Sordillo JE, Gillman MW, et al. Peanut allergy prevalence among school-age children in a US cohort not selected for any disease. J Allergy Clin Immunol. 2014;134(3):753-5

Campbell DE, Boyle RJ, Thornton CA, Prescott SL. Mechanisms of Allergic Disease – Environmental and genetic determinants for the development of allergy. Clin Exp Allergy. 2015

Della Giustina A, Landi M, Bellini F, Bosoni M, Ferrante G, Onorari M, et al. Vitamin D, allergies and asthma: focus on pediatric patients. World Allergy Organ J. 2014;7(1):27

Ly NP, Litonjua A, Gold DR, Celedon JC. Gut microbiota, probiotics, and vitamin D: interrelated exposures influencing allergy, asthma, and obesity? J Allergy Clin Immunol. 2011;127(5):1087-94; quiz 95-6

Maksimova OV, Gervazieva VB, Zverev VV. [Intestine microbiota and allergic diseases]. Zh Mikrobiol Epidemiol Immunobiol. 2014(3):49-60

Prescott SL. Early-life environmental determinants of allergic diseases and the wider pandemic of inflammatory noncommunicable diseases. J Allergy Clin Immunol. 2013;131(1):23-30

Taylor-Black SA, Mehta H, Weiderpass E, Boffetta P, Sicherer SH, Wang J. Prevalence of food allergy in New York City school children. Ann Allergy Asthma Immunol. 2014;112(6):554-6 e1.

Tsabouri S, Priftis KN, Chaliasos N, Siamopoulou A. Modulation of gut microbiota downregulates the development of food allergy in infancy. Allergol Immunopathol (Madr). 2014;42(1):69-77

Books:

Bock, Kenneth. Healing the New Childhood Epidemics: Autism, ADHD, Asthma, and Allergies: The Groundbreaking Program for the 4-A Disorders. New York, NY. Ballantine Books, 2008

Asthma

Azad, Meghan B., et al. Perinatal Programming of Asthma: The Role of Gut Microbiota. Clin Dev Immunol. 2012; 2012: 932072.

Brown, S.D., Baxter, K.M., Stephenson, S.T., Esper, A.M., Brown, L.A., Fitzpatrick, A.M. Airway TGFbeta1 and oxidant stress in children with severe asthma: association with airflow limitation. Allergy Clin Immunol. 2012;129(2):388-96, 96 e1-8

Bunyavanich, S., Schadt, E.E. Systems biology of asthma and allergic diseases: a multiscale approach. J Allergy Clin Immunol. 2015;135(1):31-42

Chauhan, B.F., Chartrand, C., Ducharme, F.M. Intermittent versus daily inhaled corticosteroids for persistent asthma in children and adults. Cochrane Database Syst Rev. 2013;2:CD009611

Checkley, W., Robinson, C.L., Baumann, L.M., Hansel, N.N., Romero, K.M., Pollard, S.L., et al. 25-hydroxy vitamin D levels are associated with childhood asthma in a population-based study in Peru. Clin Exp Allergy. 2015 Jan;45(1):273–82

D’Auria, E., Miraglia, D., Giudice, M., Barberi, S., Mandelli, M., Verduci, E., Leonardi, S., et al. Omega-3 fatty acids and asthma in children. Allergy Asthma Proc. 2014;35(3):233-40

Della Giustina, A., Landi, M., Bellini, F., Bosoni, M., Ferrante, G., Onorari, M., et al. Vitamin D, allergies and asthma: focus on pediatric patients. World Allergy Organ J. 2014;7(1):27

Desai, J.R., Wu, P., Nichols, G.A., Lieu, T.A., O’Connor, P.J. Diabetes and asthma case identification, validation, and representativeness when using electronic health data to construct registries for comparative effectiveness and epidemiologic research. Med Care. 2012;50 Suppl:S30-5

Fabian E., Poloskey, P., Kosa, L., Elmadfa, I., Rethy, L.A. Nutritional supplements and plasma antioxidants in childhood asthma. Wien Klin Wochenschr. 2013;125(11-12):309-15

Frieri, M. Asthma linked with rhinosinusitis: An extensive review. Allergy Rhinol (Providence). 2014;5(1):41-9

HGuo, C.H., Liu, P.J., Lin, K.P., Chen, P.C. Nutritional supplement therapy improves oxidative stress, immune response, pulmonary function, and quality of life in allergic asthma patients: an open-label pilot study. Altern Med Rev. 2012;17(1):42-56

Hansel, T.T., Johnston, S.L., Openshaw, P.J. Microbes and mucosal immune responses in asthma. Lancet. 2013;381(9869):861-73

Jolliffe, D.A., et al. Vitamin D supplementation to prevent asthma exacerbations: a systematic review and meta-analysis of individual participant data. Lancet Respir Med. 2017 Nov;5(11):881-890.

Lang, J.E., Blake, K.V. Role of biomarkers in understanding and treating children with asthma: towards personalized care. Pharmgenomics Pers Med. 2013;6:73-84

Lessa, N., Murray, M.L., Curran, S., Wong, I.C. Asthma and suicide-related adverse events: a review of observational studies. Eur Respir Rev. 2011;20(122):287-92

Litonjua, A.A. Childhood asthma may be a consequence of vitamin D deficiency. Curr Opin Allergy Clin Immunol. 2009;9(3):202-7

Ly, N.P., Litonjua, A., Gold, D.R., Celedon, J.C. Gut microbiota, probiotics, and vitamin D: interrelated exposures influencing allergy, asthma, and obesity? J Allergy Clin Immunol. 2011;127(5):1087-94; quiz 95-6

Martineau, A.R., et al. “Vitamin D for the management of asthma.” Cochrane Library, 2016 DOI: 10.1002/14651858.CD011511.pub2

McCloud, E., Papoutsakis, C. A medical nutrition therapy primer for childhood asthma: current and emerging perspectives. J Am Diet Assoc. 2011 Jul;111(7):1052–64

McCormack, M.C., Breysse, P.N., Matsui, E.C., Hansel, N.N., Peng, R.D., Curtin-Brosnan, J., et al. Indoor particulate matter increases asthma morbidity in children with non-atopic and atopic asthma. Ann Allergy Asthma Immunol. 2011;106(4):308-15

Norton, R.L., Hoffmann, P.R. Selenium and asthma. Mol Aspects Med. 2012;33(1):98-106

Orivuori, L., Mustonen, K., de Goffau, M.C., Hakala, S., Paasela, M., Roduit, C., et al. High level of fecal calprotectin at age 2 months as a marker of intestinal inflammation predicts atopic dermatitis and asthma by age 6. Clin Exp Allergy. 2015

Pfeffer, P.E., Mann, E.H., Hornsby, E., Chambers, E.S., Chen, Y.H., Rice, L., et al. Vitamin D influences asthmatic pathology through its action on diverse immunological pathways. Ann Am Thorac Soc. 2014;11 Suppl 5:S314-21

Propp, P., Becker, A. Prevention of asthma: where are we in the 21st century? Expert Rev Clin Immunol. 2013;9(12):1267-78

Searing, D.A., Zhang, Y., Murphy, J.R., Hauk, P.J., Goleva, E., Leung, D.Y. Decreased serum vitamin D levels in children with asthma are associated with increased corticosteroid use. J Allergy Clin Immunol. 2010;125(5):995-1000

Wlasiuk, G., Vercelli, D. The farm effect, or: when, what and how a farming environment protects from asthma and allergic disease. Curr Opin Allergy Clin Immunol. 2012;12(5):461-6

Books:

Bock, Kenneth. Healing the New Childhood Epidemics: Autism, ADHD, Asthma, and Allergies: The Groundbreaking Program for the 4-A Disorders. New York, NY. Ballantine Books, 2008.

Autism Spectrum Disorders

Adams, J.B., Audhya, T., McDonough-Means, S., Rubin, R.A., Quig, D., Geis, E., et al. Effect of a vitamin/mineral supplement on children and adults with autism. BMC Pediatr. 2011;11:111

Adams, J.B., et al. Comprehensive Nutritional and Dietary Intervention for Autism Spectrum Disorder-A Randomized, Controlled 12-Month Trial. Nutrients. 2018 Mar 17;10(3).

Alabdali, A., Al-Ayadhi, L., El-Ansary, A. A key role for an impaired detoxification mechanism in the etiology and severity of autism spectrum disorders. Behav Brain Funct. 2014;10:14

Alabdali, A., Al-Ayadhi, L., El-Ansary, A. Association of social and cognitive impairment and biomarkers in autism spectrum disorders. J Neuroinflammation. 2014;11:4

Barrett, B. Substantial lifelong cost of autism spectrum disorder. J Pediatr. 2014;165(5):1068-9

Bateman, C. Autism–mitigating a global epidemic. S Afr Med J. 2013;103(5):276-7

Bitsika, V., Sharpley, C.F., Andronicos, N.M., Agnew, L.L. Hypothalamus-pituitary-adrenal axis daily fluctuation, anxiety and age interact to predict cortisol concentrations in boys with an autism spectrum disorder. Physiol Behav. 2015;138:200-7

Bouder, J.N., Spielman, S., Mandell, D.S. Brief report: Quantifying the impact of autism coverage on private insurance premiums. J Autism Dev Disord. 2009;39(6):953-7

Bradstreet, J.J., Smith, S., Baral M., Rossignol, D.A. Biomarker-guided interventions of clinically relevant conditions associated with autism spectrum disorders and attention deficit hyperactivity disorder. Altern Med Rev. 2010;15(1):15-32

Brown, C.M., Austin, D.W., Busija, L. Observable essential fatty acid deficiency markers and autism spectrum disorder. Breastfeed Rev. 2014;22(2):21-6

Buescher, A.V., Cidav, Z., Knapp, M., Mandell, D.S. Costs of autism spectrum disorders in the United Kingdom and the United States. JAMA Pediatr. 2014;168(8):721-8

Bull, G., Shattock, P., Whiteley, P., Anderson, R., Groundwater, P.W., Lough, J.W., et al. Indolyl-3-acryloylglycine (IAG) is a putative diagnostic urinary marker for autism spectrum disorders. Med Sci Monit. 2003;9(10):CR422-5

Critchfield, J.W., van Hemert, S., Ash, M., Mulder, L., Ashwood, P. The potential role of probiotics in the management of childhood autism spectrum disorders. Gastroenterol Res Pract. 2011;2011:161358

Cubala-Kucharska M. The review of most frequently occurring medical disorders related to aetiology of autism and the methods of treatment. Acta Neurobiol Exp (Wars). 2010;70(2):141-6

Darling, A.L., et al. “Association between maternal vitamin D status in pregnancy and neurodevelopmental outcomes in childhood: results from the Avon Longitudinal Study of Parents and Children (ALSPAC).Br J Nutr 2017 Jun;117(12):1682-1692.

Dave, D., Fernandez, J.M., National Bureau of Economic Research. The effect of an increase in autism prevalence on the demand for auxiliary healthcare workers : evidence from California. Cambridge, MA: National Bureau of Economic Research; 2012. 37 p.p.

de Magistris, L., Familiari, V., Pascotto, A., Sapone, A., Frolli, A., Iardino, P., et al. Alterations of the intestinal barrier in patients with autism spectrum disorders and in their first-degree relatives. J Pediatr Gastroenterol Nutr. 2010;51(4):418-24

Deth, R., Muratore, C., Benzecry, J., Power-Charnitsky, V.A., Waly, M. How environmental and genetic factors combine to cause autism: A redox/methylation hypothesis. Neurotoxicology. 2008;29(1):190-201

Elamin, N.E., Al-Ayadhi, L.Y. Brain autoantibodies in autism spectrum disorder. Biomark Med. 2014;8(3):345-52

El-Ansary, A., Al-Ayadhi, L. Neuroinflammation in autism spectrum disorders. J Neuroinflammation. 2012;9:265.

El-Ansary, A., Al-Ayadhi, L. Lipid mediators in plasma of autism spectrum disorders. Lipids Health Dis. 2012;11:160.

Faber, S., Zinn, G.M., Boggess, A, Fahrenholz, T., Kern, J.C. 2nd, Kingston, H.M. A cleanroom sleeping environment’s impact on markers of oxidative stress, immune dysregulation, and behavior in children with autism spectrum disorders. BMC Complement Altern Med. 2015;15:71

Frustaci, A., Neri, M., Cesario, A., Adams, J.B., Domenici, E., Dalla Bernardina, B., et al. Oxidative stress-related biomarkers in autism: systematic review and meta-analyses. Free Radic Biol Med. 2012;52(10):2128-41

Frye, R.E., Delatorre, R., Taylor, H., Slattery, J., Melnyk, S., Chowdhury, N., et al. Redox metabolism abnormalities in autistic children associated with mitochondrial disease. Transl Psychiatry. 2013;3:e273

Frye, R.E., James, S.J. Metabolic pathology of autism in relation to redox metabolism. Biomark Med. 2014;8(3):321-30

Gabriele, S., Sacco, R., Persico, A.M. Blood serotonin levels in autism spectrum disorder: a systematic review and meta-analysis. Eur Neuropsychopharmacol. 2014;24(6):919-29

Gadow, K.D., Roohi, J., DeVincent, C.J., Kirsch, S., Hatchwell, E. Association of COMT (Val158Met) and BDNF (Val66Met) gene polymorphisms with anxiety, ADHD and tics in children with autism spectrum disorder. J Autism Dev Disord. 2009;39(11):1542-51

Gadow, K.D., Devincent, C.J., Olvet, D.M., Pisarevskaya, V., Hatchwell, E. Association of DRD4 polymorphism with severity of oppositional defiant disorder, separation anxiety disorder and repetitive behaviors in children with autism spectrum disorder. Eur J Neurosci. 2010;32(6):1058-65

Gebril, O.H., Meguid, N.A. HFE gene polymorphisms and the risk for autism in Egyptian children and impact on the effect of oxidative stress. Dis Markers. 2011;31(5):289-94

Geier, D.A., Kern, J.K., Geier, M.R. The biological basis of autism spectrum disorders: Understanding causation and treatment by clinical geneticists. Acta Neurobiol Exp (Wars). 2010;70(2):209-26

Ghanizadeh, A. Increased glutamate and homocysteine and decreased glutamine levels in autism: a review and strategies for future studies of amino acids in autism. Dis Markers. 2013;35(5):281-6

Goldani, A.A., Downs, S.R., Widjaja, F., Lawton, B., Hendren, R.L. Biomarkers in autism. Front Psychiatry. 2014;5:100

Guyol, G. Who’s crazy here?: Steps for recovery without drugs for: ADD/ADHD, addiction & eating disorders, anxiety & PTSD, depression, bipolar disorder, schizophrenia, autism. 1st U.S. ed. Stonington, CT: Ajoite Pub.; 2010. 123 p.p.

Herbert, M.R., Russo, J.P., Yang, S., Roohi, J., Blaxill, M., Kahler, S.G., et al. Autism and environmental genomics. Neurotoxicology. 2006;27(5):671-84

Heyer, N.J., Echeverria, D., Woods, J.S. Disordered porphyrin metabolism: a potential biological marker for autism risk assessment. Autism Res. 2012;5(2):84-92

Howsmon, D. P., Vargason, T. , Rubin, R. A., Delhey, L. , Tippett, M. , Rose, S. , Bennuri, S. C., Slattery, J. C., Melnyk, S. , James, S. J., Frye, R. E. and Hahn, J. (2018), Multivariate techniques enable a biochemical classification of children with autism spectrum disorder versus typically‐developing peers: A comparison and validation study. Bioengineering & Translational Medicine. . doi:10.1002/btm2.10095

James, S.J., Cutler, P., Melnyk, S., Jernigan, S., Janak, L., Gaylor, D.W., et al. Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism. Am J Clin Nutr. 2004;80(6):1611-7

Jyonouchi, H., Geng, L., Ruby, A., Zimmerman-Bier, B. Dysregulated innate immune responses in young children with autism spectrum disorders: their relationship to gastrointestinal symptoms and dietary intervention. Neuropsychobiology. 2005;51(2):77-85

Kaluzna-Czaplinska, J., Zurawicz, E., Struck, W., Markuszewski, M. Identification of organic acids as potential biomarkers in the urine of autistic children using gas chromatography/mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2014;966:70-6

Kern, J.K., Geier, D.A., Adams, J.B., Geier, M.R. A biomarker of mercury body-burden correlated with diagnostic domain specific clinical symptoms of autism spectrum disorder. Biometals. 2010;23(6):1043-51

Kuwabara, H., Yamasue, H., Koike, S., Inoue, H., Kawakubo, Y., Kuroda, M., et al. Altered metabolites in the plasma of autism spectrum disorder: a capillary electrophoresis time-of-flight mass spectroscopy study. PLoS One. 2013;8(9):e73814

Lavelle, T.A., Weinstein, M.C., Newhouse, J.P., Munir, K., Kuhlthau, K.A., Prosser, L.A. Economic burden of childhood autism spectrum disorders. Pediatrics. 2014;133(3):e520-9

Li, S.O., Wang, J.L., Bjorklund, G., Zhao, W.N., Yin, C.H. Serum copper and zinc levels in individuals with autism spectrum disorders. Neuroreport. 2014;25(15):1216-20

Maher, P. Methylglyoxal, advanced glycation end products and autism: is there a connection? Med Hypotheses. 2012;78(4):548-52

Momeni, N., Bergquist, J., Brudin, L., Behnia, F., Sivberg, B., Joghataei, M.T., et al. A novel bloodbased biomarker for detection of autism spectrum disorders. Transl Psychiatry. 2012;2:e91

Nankova ,B.B., Agarwal, R., MacFabe, D.F., La Gamma, E.F. Enteric bacterial metabolites propionic and butyric acid modulate gene expression, including CREB-dependent catecholaminergic neurotransmission, in PC12 cells–possible relevance to autism spectrum disorders. PLoS One. 2014;9(8):e103740

Ngounou Wetie, A.G., Wormwood, K., Thome, J., Dudley, E., Taurines, R., Gerlach, M., et al. A pilot proteomic study of protein markers in autism spectrum disorder. Electrophoresis. 2014;35(14):2046-54

Noto, A., Fanos, V., Barberini, L., Grapov, D., Fattuoni, C., Zaffanello, M., et al. The urinary metabolomics profile of an Italian autistic children population and their unaffected siblings. J Matern Fetal Neonatal Med. 2014;27 Suppl 2:46-52

Ozonoff, S., et al. Onset patterns in autism: Variation across informants, methods, and timing. Autism Res. 2018 Mar 10.

Patrick, R.P., Ames, B.N. Vitamin D hormone regulates serotonin synthesis. Part 1: relevance for autism. FASEB J. 2014;28(6):2398-413

Peterson, B.S., Goh, S., Dong, Z. Brain lactate as a potential biomarker for comorbid anxiety disorder in autism spectrum disorder-reply. JAMA Psychiatry. 2015;72(2):190-1

Ranjbar, A., Rashedi, V., Rezaei, M. Comparison of urinary oxidative biomarkers in Iranian children with autism. Res Dev Disabil. 2014;35(11):2751-5

Ratajczak, H.V. Theoretical aspects of autism: biomarkers–a review. J Immunotoxicol. 2011;8(1):80-94

Reynolds, A., Krebs, N.F., Stewart, P.A., Austin, H., Johnson, S.L., Withrow, N., et al. Iron status in children with autism spectrum disorder. Pediatrics. 2012;130 Suppl 2:S154-9

Rutter, M. Changing concepts and findings on autism. J Autism Dev Disord. 2013;43(8):1749-57

Ruggeri, B., Sarkans, U., Schumann, G., Persico, A.M. Biomarkers in autism spectrum disorder: the old and the new. Psychopharmacology (Berl). 2014;231(6):1201-16

Spilioti, M., Evangeliou, A.E., Tramma, D., Theodoridou, Z., Metaxas, S., Michailidi, E., et al. Evidence for treatable inborn errors of metabolism in a cohort of 187 Greek patients with autism spectrum disorder (ASD). Front Hum Neurosci. 2013;7:858

Theoharides, T.C. Is a subtype of autism an allergy of the brain? Clin Ther. 2013; 35(5):584-91

Thomas, R.H., Meeking, M.M., Mepham, J.R., Tichenoff, L., Possmayer, F., Liu, S., et al. The enteric bacterial metabolite propionic acid alters brain and plasma phospholipid molecular species: further development of a rodent model of autism spectrum disorders. J Neuroinflammation. 2012;9:153

Vuillermot, S., et al. “Vitamin D treatment during pregnancy prevents autism-related phenotypes in a mouse model of maternal immune activation.Mol Autism. 2017 Mar 7;8:9.

Wang, L., Conlon, M.A., Christophersen, C.T., Sorich, M.J., Angley, M.T. Gastrointestinal microbiota and metabolite biomarkers in children with autism spectrum disorders. Biomark Med. 2014;8(3):331-44

Woodman, A.C., Smith, L.E., Greenberg, J.S., Mailick, M.R. Change in autism symptoms and maladaptive behaviors in adolescence and adulthood: the role of positive family processes. J Autism Dev Disord. 2015;45(1):111-26

Wu, D.M., et al. “Relationship Between Neonatal Vitamin D at Birth and Risk of Autism Spectrum Disorders: the NBSIB Study.J Bone Miner Res. 2018 Mar;33(3):458-466.

Books:

Bock, Kenneth. Healing the New Childhood Epidemics: Autism, ADHD, Asthma, and Allergies: The Groundbreaking Program for the 4-A Disorders. New York, NY. Ballantine Books, 2008.

Brandes, Bonnie. The Symphony of Reflexes: Interventions for Human Development, Autism, ADHD, CP, and Other Neurological Disorders, 2016.

Campbell-McBride, Natasha. Gut and Psychology Syndrome: Natural Treatment for Autism, Dyspraxia, A.D.D., Dyslexia, A.D.H.D., Depression, Schizophrenia, 2010.

Giustra-Kozek, Jennifer. Healing without hurting: treating ADHD, apraxia, and autism spectrum disorders naturally and effectively without harmful medication. Howard Beach, NY: Changing Lives Press, 2014.

Herbert, Martha, Weintraub Karen. The Autism Revolution: Whole-Body Strategies for Making Life All It Can Be. New York: Ballantine Books; 2012.

Hong, Maria Rickert. “Almost Autism: Recovering Children from Sensory Processing Disorder, A Reference for Parents and Practitioners.” 2014.

Kaufman, Raun K. Autism breakthrough: the groundbreaking method that has helped families all over the world. First edition. ed. New York: St. Martin’s Press; 2014. x, 353 p.p.

Lemer, Patricia S. Outsmarting Autism: The Ultimate Guide to Management, Healing and Prevention for Individuals with Autism Spectrum Disorders. Tarentum, PA, Word Association Publishers, 2014.

Romaniec, Mary. Victory Over Autism: Lessons on Raising an Autism-Free Child. New York, NY: Skyhorse Publishing, 2015.

Sears, Robert W. The Autism Book: What Every Parent Needs to Know about Early Detection, Treatment, Recovery, and Prevention. 1st ed. New York, NY: Little, Brown, 2010.

Seroussi, Karyn. Unraveling the Mystery of Autism and Pervasive Developmental Disorder: A Mother’s Story of Research and Recovery. New York: Simon & Schuster, 2000.

Autoimmune Disorders

de Goffau, M.C., Luopajarvi, K., Knip, M., Ilonen, J., Ruohtula, T., Harkonen, T., et al. Fecal microbiota composition differs between children with beta-cell autoimmunity and those without. Diabetes. 2013;62(4):1238-44

Stagi, S., Bertini, F., Cavalli, L., Matucci-Cerinic, M., Brandi, M.L., Falcini, F. Determinants of vitamin D levels in children, adolescents, and young adults with juvenile idiopathic arthritis. J Rheumatol. 2014;41(9):1884-92

Watt, T., Hegedus, L., Bjorner, J.B., Groenvold, M., Bonnema, S.J., Rasmussen, A.K., et al. Is Thyroid Autoimmunity per se a Determinant of Quality of Life in Patients with Autoimmune Hypothyroidism? Eur Thyroid J. 2012;1(3):186-92

Books:

Galland, Leo. Superimmunity for Kids: What to Feed Your Children to Keep Them Healthy Now, and Prevent Disease in Their Future. Dell, 1989.

Whittaker, Faye. Rheumatoid Remedies: A Collection of More Than 70 Pages of Nutritional and Drug-Free Options to Promote Recovery from Rheumatoid Arthritis and Associated Inflammatory Diseases. 1st ed. Kaitaia, New Zealand: Dancing Lion Press; 2009.

Breathing Issues

Brown, S.D., Baxter, K.M., Stephenson, S.T., Esper, A.M., Brown, L.A., Fitzpatrick, A.M. Airway TGFbeta1 and oxidant stress in children with severe asthma: association with airflow limitation. Allergy Clin Immunol. 2012;129(2):388-96, 96 e 1-8

Chronic/Recurrent Infections

Nsouli, T.M. The role of food allergy in serious otitis media. Ann Allergy 1991; 66:91

Books:

Dorfman, K. Cure Your Child with Food. New York, NY. Workman Publishing, 2013.

Oski, R. Don’t Drink Your Milk. 3rd Edition. TEACH Services, 2013.

Colic

Aguilera, M., Cerda-Cuellar, M., Martinez, V. Antibiotic-induced dysbiosis alters host-bacterial interactions and leads to colonic sensory and motor changes in mice. Gut Microbes. 2015;6(1):10-23

Aroniadis, O.C., Brandt, L.J. Fecal microbiota transplantation: past, present and future. Curr Opin Gastroenterol. 2013;29(1):79-84

Assa, A., Vong, L., Pinnell, L.J., Avitzur, N., Johnson-Henry, K.C., Sherman, P.M. Vitamin D deficiency promotes epithelial barrier dysfunction and intestinal inflammation. J Infect Dis. 2014;210(8):1296-305

Azad, Meghan B., et al. “Perinatal Programming of Asthma: The Role of Gut Microbiota.Clin Dev Immunol. 2012; 2012: 932072.

Bag, Ozelem, et al. “Is it infant colic or early symptom of autistic spectrum disorder?” Pediatr Int 23 Mar 2018.

Buccigrossi, V., Nicastro, E., Guarino, A. Functions of intestinal microflora in children. Curr Opin Gastroenterol. 2013;29(1):31-8

Carding, S., Verbeke, K., Vipond, D.T., Corfe, B.M., Owen, L.J. Dysbiosis of the gut microbiota in disease. Microb Ecol Health Dis. 2015;26:26191

Cucchiara, S., Stronati, L., Aloi, M. Interactions between intestinal microbiota and innate immune system in pediatric inflammatory bowel disease. J Clin Gastroenterol. 2012;46 Suppl:S64-6

Fukuda, K., Fujita, Y. Determination of the discriminant score of intestinal microbiota as a biomarker of disease activity in patients with ulcerative colitis. BMC Gastroenterol. 2014;14:49.

Galland, L. The gut microbiome and the brain. J Med Food 2014; 17(12): 1261-72

Guandalini, S. Are probiotics or prebiotics useful in pediatric irritable bowel syndrome or inflammatory bowel disease? Front Med (Lausanne). 2014;1:23

Guandalini, S., Cernat, E., Moscoso, D. Prebiotics and probiotics in irritable bowel syndrome and inflammatory bowel disease in children. Benef Microbes. 2015;6(2):209-17

Jakobsen, C., Paerregaard, A., Munkholm, P., Wewer, V. Environmental factors and risk of developing paediatric inflammatory bowel disease — a population based study. 2007-2009. J Crohns Colitis. 2013;7(1):79-88

Manichanh, C., Borruel, N., Casellas, F., Guarner, F. The gut microbiota in IBD. Nat Rev Gastroenterol Hepatol. 2012;9(10):599-608

Savino, F., et al. Lactobacillus reuteri (American Type Culture Collection Strain 55730) versus simethicone in the treatment of infantile colic: a prospective randomized study. Pediatrics. 2007 Jan;119(1):e124-30.

Sela, D.A., Mills, D.A. The marriage of nutrigenomics with the microbiome: the case of infant associated bifidobacteria and milk. Am J Clin Nutr. 2014;99(3):697S-703S

Stiemsma, Leah T., et al. The Role of the Microbiome in the Developmental Origins of Health and Disease. Pediatrics, Mar 2018.

West, C.E., Renz, H., Jenmalm, M.C., Kozyrskyj, A.L., Allen, K.J., Vuillermin, P., et al. The gut microbiota and inflammatory noncommunicable diseases: associations and potentials for gut microbiota therapies. J Allergy Clin Immunol. 2015;135(1):3-13; quiz 4.

Constipation and Diarrhea

An, H.M., et al. Efficacy of Lactic Acid Bacteria (LAB) supplement in management of constipation among nursing home residents.  Nutr J. 2010 Feb 5;9:5.

Chitkara, D.K., et al. Abnormalities in gastrointestinal motility are associated with diseases of oxidative phosphorylation in children.  Am J Gastroenterol. 2003 Apr;98(4):871-7.

Chmielewska, A., et al. Systematic review of randomised controlled trials:  probiotics for functional constipation. World J Gastroenterol 2010 Jan 7;16(1):69-75.

Greene. J.G., et al. Delayed gastric emptying and enteric nervous system dysfunction in the rotenone model of Parkinson’s disease.  Exp. Neurol. 2009 Jul;218(1):154-61.

Higashikawa, F., et al. Improvement of constipation and liver function by plant-derived lactic acid bacteria:  a double-blind, randomized trial. Nutrition 2010 Apr;26(4):367-74.

Lee, H.R., et al. Bacteria and irritable bowel syndrome:  the evidence for small intestinal bacterial overgrowth.  Curr Gastroenterol Rep. 2006 Aug;8(4):305-11.

Madrid, A.M., et al. Small intestinal bacterial overgrowth in patients with functional gastrointestinal diseases.  Rev Med Chil. 2007 Oct;135(10):1245-52.

Martens, U., et al. Probiotic treatment of irritable bowel syndrome in children. Ger Med Sci. 2010 Mar 2;8:Doc07.

Pimintel, M., et al. Irritable Bowel Syndrome:  Bacterial Overgrowth–What’s Known and What to Do.  Curr Treat Options Gastroenterol. 2007 Aug;10(4):328-37.

Dyslexia

Baker, S.M. (1985). A biochemical approach to the problem of dyslexia. Journal of Learning Disabilities, 18(10): 581-584.

Johnson, Kathy. Dyslexia: Recognizing, Screening and Treating. Albany, NY. Pyramid of Potential, 2014.

Vision and Dyslexia. College of Optometrists in Vision Development. 2008

Emotional/Behavioral/Mood Symptoms

Atladottir, H.O., Gyllenberg, D., Langridge, A., Sandin, S., Hansen, S.N., Leonard, H., et al. The increasing prevalence of reported diagnoses of childhood psychiatric disorders: a descriptive multinational comparison. Eur Child Adolesc Psychiatry. 2015;24(2):173-83.

Berk, M., Williams, L.J., Jacka, F.N., O’Neil, A., Pasco, J.A., Moylan, S., et al. So depression is an inflammatory disease, but where does the inflammation come from? BMC Med.2013;11:200.

Berry, E.A., Heaton, P.T., Kelton, C.M. National estimates of the inpatient burden of pediatric bipolar disorder in the United States. J Ment Health Policy Econ. 2011;14(3):115-23.

Bayer, J.K., Rapee, R.M., Hiscock, H., Ukoumunne, O.C., Mihalopoulos, C., Clifford, S., et al. The Cool Little Kids randomised controlled trial: population-level early prevention for anxiety disorders. BMC Public Health. 2011;11:11.

Bitsko, R.H., et al. Epidemiology and Impact of Health Care Provider-Diagnosed Anxiety and Depression Among US Children. J Dev Behav Pediatr 2018 Apr 24. doi: 10.1097/DBP.0000000000000571.

Bonnot, O., Inaoui, R., Raffin-Viard, M., Bodeau, N., Coussieu, C., Cohen, D. Children and adolescents with severe mental illness need vitamin D supplementation regardless of disease or treatment. J Child Adolesc Psychopharmacol. 2011;21(2):157-61.

Ceylan, M.F., Guney, E., Alisik, M., Ergin, M., Dinc, G.S., Goker, Z., et al. Lipid peroxidation markers in children with anxiety disorders and their diagnostic implications. Redox Rep. 2014;19(2):92-6.

Cohen-Cline, H., Turkheimer, E., Duncan, G.E. Access to green space, physical activity and mental health: a twin study. J Epidemiol Community Health. 2015 Jun;69(6):523-9.

Costello, E.J., Foley, D.L., Angold, A. 10-year research update review: the epidemiology of child and adolescent psychiatric disorders: II. Developmental epidemiology. J Am Acad Child Adolesc Psychiatry. 2006 Jan;45(1):8–25.

Dusetzina, S.B., Farley, J.F., Weinberger, M., Gaynes, B.N., Sleath, B., Hansen, R.A. Treatment use and costs among privately insured youths with diagnoses of bipolar disorder. Psychiatr Serv. 2012;63(10):1019-25.

Guney, E., Fatih, Ceylan M., Tektas, A., Alisik, M., Ergin, M., Goker, Z., et al. Oxidative stress in children and adolescents with anxiety disorders. J Affect Disord. 2014;156:62-6.

Fernandes, A.C., Cloete, D., Broadbent, M.T., Hayes, R.D., Chang, C.K., Jackson, R.G., et al. Development and evaluation of a de-identification procedure for a case register sourced from mental health electronic records. BMC Med Inform Decis Mak. 2013;13:71.

Hepgul, N., Cattaneo, A., Zunszain, P.A., Pariante, C.M. Depression pathogenesis and treatment: what can we learn from blood mRNA expression? BMC Med. 2013;11:28.

Karakula, H., Opolska, A., Kowal, A., Domanski, M., Plotka, A., Perzynski, J. [Does diet affect our mood? The significance of folic acid and homocysteine]. Pol Merkur Lekarski. 2009;26(152):136-41.

Leuchter, A.F., Hunter, A.M., Krantz, D.E., Cook, I.A. Intermediate phenotypes and biomarkers of treatment outcome in major depressive disorder. Dialogues Clin Neurosci. 2014;16(4):525-37.

Marazziti, D., Baroni, S., Picchetti, M., Landi, P., Silvestri, S., Vatteroni, E., et al. Psychiatric disorders and mitochondrial dysfunctions. Eur Rev Med Pharmacol Sci. 2012;16(2):270-5.

Mitchell, E.S., Conus, N., Kaput, J. B vitamin polymorphisms and behavior: evidence of associations with neurodevelopment, depression, schizophrenia,bipolar disorder and cognitive decline. Neurosci Biobehav Rev. 2014;47:307-20.

Ostiguy, C.S., Ellenbogen, M.A., Walker, C.D., Walker, E.F., Hodgins, S. Sensitivity to stress among the offspring of parents with bipolar disorder: a study of daytime cortisol levels. Psychol Med. 2011;41(11):2447-57.

Rollins, B., Martin, M.V., Sequeira, P.A., Moon, E.A., Morgan, L.Z., Watson, S.J., et al. Mitochondrial variants in schizophrenia, bipolar disorder, and major depressive disorder. PLoS One. 2009;4(3):e4913.

Rook, G.A., Raison, C.L., Lowry, C.A. Microbiota, immunoregulatory old friends and psychiatric disorders. Adv Exp Med Biol. 2014;817:319-56.

Thompson, L., Kemp, J., Wilson, P., Pritchett, R., Minnis, H., Toms-Whittle, L., et al. What have birth cohort studies asked about genetic, pre- and perinatal exposures and child and adolescent onset mental health outcomes? A systematic review. Eur Child Adolesc Psychiatry. 2010;19(1):1-15.

Van Meter, A.R., Henry, D.B., West, A.E. What goes up must come down: the burden of bipolar depression in youth. J Affect Disord. 2013;150(3):1048-54.

Books:

Brogan K. A Mind of Your Own. The Truth About Depression and How Women Can Heal Their Bodies to Reclaim Their Lives. New York, Harper, 2016.

Campbell-McBride, Natasha. Gut and Psychology Syndrome: Natural Treatment for Autism, Dyspraxia, A.D.D., Dyslexia, A.D.H.D., Depression, Schizophrenia. 2010.

Doman, Glenn. What To Do About Your Brain-Injured Child, or Your Brain-Damaged, Mentally Retarded, Mentally Deficient, Cerebral-Palsied, Emotionally Disturbed, Spastic, Flaccid, Rigid, Epileptic, Autistic, Athetoid, Hyperactive, Down’s Child. Garden City, New York. Doubleday; 1990.

Guyol, G. Who’s Crazy Here?: Steps for Recovery Without Drugs for ADD/ADHD, Addiction & Eating Disorders, Anxiety & PTSD, Depression, Bipolar Disorder, Schizophrenia, Autism. 1st U.S. ed. Stonington, CT: Ajoite Pub.; 2010.

Hyman, Mark. The UltraMind Solution: Fix Your Broken Brain by Healing Your Body First: The Simple Way to Defeat Depression, Overcome Anxiety and Sharpen Your Mind. 1st Scribner hardcover ed. New York: Scribner; 2008.

Gastrointestinal Disorders

Aguilera, M., Cerda-Cuellar, M., Martinez, V. Antibiotic-induced dysbiosis alters host-bacterial interactions and leads to colonic sensory and motor changes in mice. Gut Microbes. 2015;6(1):10-23

Aroniadis, O.C., Brandt, L.J. Fecal microbiota transplantation: past, present and future. Curr Opin Gastroenterol. 2013;29(1):79-84

Assa, A., Vong, L., Pinnell, L.J., Avitzur, N., Johnson-Henry, K.C., Sherman, P.M. Vitamin D deficiency promotes epithelial barrier dysfunction and intestinal inflammation. J Infect Dis. 2014;210(8):1296-305

Buccigrossi, V., Nicastro, E., Guarino, A. Functions of intestinal microflora in children. Curr Opin Gastroenterol. 2013;29(1):31-8

Carding, S., Verbeke, K., Vipond, D.T., Corfe, B.M., Owen, L.J. Dysbiosis of the gut microbiota in disease. Microb Ecol Health Dis. 2015;26:26191

Cucchiara, S., Stronati, L., Aloi, M. Interactions between intestinal microbiota and innate immune system in pediatric inflammatory bowel disease. J Clin Gastroenterol. 2012;46 Suppl:S64-6

Fukuda, K., Fujita, Y. Determination of the discriminant score of intestinal microbiota as a biomarker of disease activity in patients with ulcerative colitis. BMC Gastroenterol. 2014;14:49.

Galland, L. The gut microbiome and the brain. J Med Food 2014; 17(12): 1261-72

Guandalini, S. Are probiotics or prebiotics useful in pediatric irritable bowel syndrome or inflammatory bowel disease? Front Med (Lausanne). 2014;1:23

Guandalini, S., Cernat, E., Moscoso, D. Prebiotics and probiotics in irritable bowel syndrome and inflammatory bowel disease in children. Benef Microbes. 2015;6(2):209-17

Jakobsen, C., Paerregaard, A., Munkholm, P., Wewer, V. Environmental factors and risk of developing paediatric inflammatory bowel disease — a population based study. 2007-2009. J Crohns Colitis. 2013;7(1):79-88

Manichanh, C., Borruel, N., Casellas, F., Guarner, F. The gut microbiota in IBD. Nat Rev Gastroenterol Hepatol. 2012;9(10):599-608

Savino, F., et al. Lactobacillus reuteri (American Type Culture Collection Strain 55730) versus simethicone in the treatment of infantile colic: a prospective randomized study. Pediatrics. 2007 Jan;119(1):e124-30.

Sela, D.A., Mills, D.A. The marriage of nutrigenomics with the microbiome: the case of infant associated bifidobacteria and milk. Am J Clin Nutr. 2014;99(3):697S-703S

West, C.E., Renz, H., Jenmalm, M.C., Kozyrskyj, A.L., Allen, K.J., Vuillermin, P., et al. The gut microbiota and inflammatory noncommunicable diseases: associations and potentials for gut microbiota therapies. J Allergy Clin Immunol. 2015;135(1):3-13; quiz 4

Books:

Campbell-McBride, Natasha. Gut and Psychology Syndrome: Natural Treatment for Autism, Dyspraxia, A.D.D., Dyslexia, A.D.H.D., Depression, Schizophrenia. 2010

Chutkin, Robin. The Microbiome Solution: A Radical New Way to Heal Your Body from the Inside Out.  Avery, 2016

Infections of the Ear, Nose and Throat

Frieri, M. Asthma linked with rhinosinusitis: An extensive review. Allergy Rhinol (Providence). 2014;5(1):41-9

Nsouli, T.M. The role of food allergy in serious otitis media. Ann Allergy 1991; 66:91

Books:

Schmidt, Michael. Healing Childhood Ear Infections. 1996.

Mitochondrial Dysfunction

Andreazza, A.C., et al. “Mitochondrial complex I activity and oxidative damage to mitochondrial proteins in the prefrontal cortex of patients with bipolar disorder.Arch Gen Psychiatry. 2010 Apr;67(4):360-8.

Balcells, Cristy. “Autism & Mitochondrial Disorders: How Much Do We Really Know?“. MitoAction.org. 29 Jan 2009

Beal, M.F., et al. “Therapeutic approaches to mitochondrial dysfunction in Parkinson’s disease.Parkinsonism Relat Disord. 2009 Dec;15 Suppl 3:S189-94.

Bradstreet, J.J., et al. “Biomarker-guided interventions of clinically relevant conditions associated with autism spectrum disorders and attention deficit hyperactivity disorder.Altern Med Rev. 2010 Apr;15(1):15-32.

Burchell, V.S., et al. “Targeting mitochondrial dysfunction in neurodegenerative disease: Part I.Expert Opin Ther Targets. 2010 Apr;14(4):369-85.

Burchell, V.S., et al. “Targeting mitochondrial dysfunction in neurodegenerative disease: Part II.Expert Opin Ther Targets. 2010 May;14(5):497-511.

Davi, Alyssa. “Has Your Child with Autistic Symptoms Been Properly Screened for a Subset of Mitochondrial Disease Known as OXPHOS?…Probably Not.” Autism File. 2010; 36.

Dehley, Leanna M., et al. “The Effect of Mitochondrial Supplements on Mitochondrial Activity in Children with Autism Spectrum Disorder.J Clin Med. 2017 Feb; 6(2): 18.

Ferrer, et al. “Early involvement of the cerebral cortex in Parkinson’s disease: convergence of multiple metabolic defects.Prog Neurobiol. 2009 Jun;88(2):89-103.

Filipek, P.A., et al. “Relative carnitine deficiency in autism.J Autism Dev Disord. 2004 Dec;34(6):615-23.

Haas, R.H., et al. “Mitochondrial disease: a practical approach for primary care physicians.Pediatrics. 2007 Dec;120(6):1326-33.

Hao, J., et al. “Mitochondrial nutrients improve immune dysfunction in the type 2 diabetic Goto-Kakizaki rats.J Cell Mol Med. 2009 Apr;13(4):701-11.

Herbert, M.R. “Contributions of the environment and environmentally vulnerable physiology to autism spectrum disorders.Curr Opin Neurol. 2010 Apr;23(2):103-10

James, S.J., et al. “Cellular and mitochondrial glutathione redox imbalance in lymphoblastoid cells derived from children with autism.FASEB J. 2009 Aug;23(8):2374-83.

Kato, T. “The role of mitochondrial dysfunction in bipolar disorder.Drug News Perspect. 2006 Dec;19(10):597-602.

Kelley, R.I. “Evaluation and Treatment of Patients with Autism and Mitochondrial Disease.” Kennedy Krieger Institute, Division of Metabolism.

Klehm, M., et al. “Clinician’s Guide to the Management of Mitochondrial Disease: A Manual for Primary Care Providers.” MitiAction.org. 2014.

Konradi, C., et al. “Molecular evidence for mitochondrial dysfunction in bipolar disorder.Arch Gen Psychiatry. 2004 Mar;61(3):300-8.

Korson, M. “Mitochondrial Disease and Patient Challenges.” MitoAction. 2008.

Leib, S., et al. “Mitochondrial Oxidative Phosphorylation (OXPHOS) Dysfunction: A Newly Emerging Category of Autistic Spectrum Disorder Information for Primary Care Physicians.” MitoAction.org. 2010.

Liu, J. “The effects and mechanisms of mitochondrial nutrient alpha-lipoic acid on improving age-associated mitochondrial and cognitive dysfunction: an overview.Neurochem Res. 2008 Jan;33(1):194-203.

Long, J., et al. “Mitochondrial decay in the of old rats: ameliorating effect of alpha-lipoic acid and acetyl-L-carnitine.Neurochem Res. 2009 Apr;34(4):755-63.

Mabalirajan, U., et al. “Effects of vitamin E on mitochondrial and asthma features in an experimental allergic murine model.J Appl Physiol (1985). 2009 Oct;107(4):1285-92.

Maes, M., et al. “Coenzyme Q10 deficiency in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is related to fatigue, autonomic and neurocognitive symptoms and is another risk factor explaining the early mortality in ME/CFS due to cardiovascular disorder.Neuro Endocrinol Lett. 2009;30(4):470-6.

Maes, M., et al. “Lower plasma Coenzyme Q10 in depression: a marker for treatment resistance and chronic fatigue in depression and a risk factor to cardiovascular disorder in that illness.Neuro Endocrinol Lett. 2009;30(4):462-9.

Morino, K., et al. “Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction.Diabetes. 2006 Dec;55 Suppl 2:S9-S15.

Noland, R.C., et al. “Carnitine insufficiency caused by aging and overnutrition compromises mitochondrial performance and metabolic control.J Biol Chem. 2009 Aug 21;284(34):22840-52.

Oliveira, G., et al. “Mitochondrial dysfunction in autism spectrum disorders: a population-based study.Dev Med Child Neurol. 2005 Mar;47(3):185-9.

Palmieri, L., et al. “Mitochondrial dysfunction in autism spectrum disorders: cause or effect?Biochim Biophys Acta. 2010 Jun-Jul;1797(6-7):1130-7.

Pastural, E., et al. “Novel plasma phospholipid biomarkers of autism: mitochondrial dysfunction as a putative causative mechanism.Prostaglandins Leukot Essent Fatty Acids. 2009 Oct;81(4):253-64.

Power, R.A., et al. “Carnitine revisited: potential use as adjunctive treatment in diabetes.Diabetologia. 2007 Apr;50(4):824-32.

Rector, R.S., et al. “Mitochondrial dysfunction precedes insulin resistance and hepatic steatosis and contributes to the natural history of non-alcoholic fatty liver disease in an obese rodent model.J Hepatol. 2010 May;52(5):727-36.

Schmidt, Charles W. “Mito-Conundrum: Unraveling Environmental Effects on Mitochondria.” Environmental Health Perspectives. 2010 July; 118(7).

Scirocco, A., et al. “Exposure of Toll-like receptors 4 to bacterial lipopolysaccharide (LPS) impairs human colonic smooth muscle cell function.J Cell Physiol. 2010 May;223(2):442-50.

Shen, W., et al. “Protective effects of R-alpha-lipoic acid and acetyl-L-carnitine in MIN6 and isolated rat islet cells chronically exposed to oleic acid.J Cell Biochem. 2008 Jul 1;104(4):1232-43.

Shekhawat, P.S., et al. “Spontaneous development of intestinal and colonic atrophy and inflammation in the carnitine-deficient jvs (OCTN2(-/-)) mice.Mol Genet Metab. 2007 Dec;92(4):315-24.

Shoffner, J., et al. “Fever Plus Mitochondrial Disease Could Be Risk Factors for Autistic Regression.J Child Neurol. 2010 Apr;25(4):429-34.

Sifroni, K.G., et al. “Mitochondrial respiratory chain in the colonic mucosal of patients with ulcerative colitis.Mol Cell Biochem. 2010 Sep;342(1-2):111-5.

Spindler, M., et al. “Coenzyme Q10 effects in neurodegenerative disease.Neuropsychiatr Dis Treat. 2009;5:597-610.

Sreekumar, R., et al. “Skeletal muscle mitochondrial dysfunction & diabetes.Indian J Med Res. 2007 Mar;125(3):399-410.

Taurines, R., et al. “Expression analyses of the mitochondrial complex I 75-kDa subunit in early onset schizophrenia and autism spectrum disorder: increased levels as a potential biomarker for early onset schizophrenia.Eur Child Adolesc Psychiatry. 2010 May;19(5):441-8.

Weissman, J.R., et al. “Mitochondrial Disease in Autism Spectrum Disorder Patients: A Cohort Analysis.PLoS One. 2008;3(11):e3815.

Zhang, H., et al. “Combined Ralpha-lipoic acid and acetyl-L-carnitine exerts efficient preventative effects in a cellular model of Parkinson’s disease.J Cell Mol Med. 2010 Jan;14(1-2):215-25.

Obesity/Diabetes

Adebayo, O., Willis, G.C. The changing face of diabetes in America. Emerg Med Clin North Am. 2014;32(2):319-27

Banerjee, S., Debnath, P., Rao, P.N., Tripathy, T.B., Adhikari, A., Debnath, P.K. Ayurveda in changing scenario of diabetes management for developing safe and effective treatment choices for the future. J Complement Integr Med. 2015

Basic, M., Butorac, A., Landeka Jurcevic, I., Bacun-Druzina, V. Obesity: genome and environment interactions. Arh Hig Rada Toksikol. 2012;63(3):395-405

Bipartisan Policy Center. Lots to lose how America’s health and obesity crisis threatens our economic future. Washington, D.C.: Bipartisan Policy Center,; 2012

Carlson, J.A., Crespo, N.C., Sallis, J.F., Patterson, R.E., Elder, J.P. Dietary-related and physical activity-related predictors of obesity in children: a 2-year prospective study. Child Obes. 2012;8(2):110-5

Choquet, H., Meyre, D. Genomic insights into early-onset obesity. Genome Med. 2010;2(6):36

Classen, J.B. Review of evidence that epidemics of type 1 diabetes and type 2 diabetes/metabolic syndrome are polar opposite responses to iatrogenic inflammation. Curr Diabetes Rev. 2012;8(6):413-8

Cortese, S., Angriman, M. Attention-deficit/hyperactivity disorder, iron deficiency, and obesity: is there a link? Postgrad Med. 2014;126(4):155-70

Desai, J.R., Wu, P., Nichols, G.A., Lieu, T.A., O’Connor, P.J. Diabetes and asthma case identification, validation, and representativeness when using electronic health data to construct registries for comparative effectiveness and epidemiologic research. Med Care. 2012;50 Suppl:S30-5

He, C., Shan, Y., Song ,W. Targeting gut microbiota as a possible therapy for diabetes. Nutr Res. 2015

Hinzmann, R., Schlaeger, C., Tran, C.T. What do we need beyond hemoglobin A1c to get the complete picture of glycemia in people with diabetes? Int J Med Sci. 2012;9(8):665-81

Kogut, S.J., Johnson, S., Higgins, T., Quilliam, B. Evaluation of a program to improve diabetes care through intensified care management activities and diabetes medication copayment reduction. J Manag Care Pharm. 2012;18(4):297-310

Kong., A.P, Xu, G., Brown, N., So, W.Y., Ma, R.C., Chan, J.C. Diabetes and its comorbidities–where East meets West. Nat Rev Endocrinol. 2013;9(9):537-47

Laron, Z. Interplay between heredity and environment in the recent explosion of type 1 childhood diabetes mellitus. Am J Med Genet. 2002;115(1):4-7

Levi, J., Segal, L.M., St. Laurent, R., Lang, A., Rayburn, J., Robert Wood Johnson Foundation., et al. F as in fat how obesity threatens America’s future : 2012. Washington, D.C.: Trust for America’s Health; 2012

Ly, N.P., Litonjua, A., Gold, D.R., Celedon, J.C. Gut microbiota, probiotics, and vitamin D: interrelated exposures influencing allergy, asthma, and obesity? J Allergy Clin Immunol. 2011;127(5):1087-94; quiz 95-6

Magrone, T., Jirillo, E. Childhood obesity: immune response and nutritional approaches. Front Immunol. 2015;6:76

Pacal, L., Varvarovska, J., Rusavy, Z., Lacigova, S., Stetina, R., Racek, J., et al. Parameters of oxidative stress, DNA damage and DNA repair in type 1 and type 2 diabetes mellitus. Arch Physiol Biochem. 2011;117(4):222-30

Pulgaron, E.R. Childhood obesity: a review of increased risk for physical and psychological comorbidities. Clin Ther. 2013;35(1):A18-32

Renteria, I., Arenas Berumen, E., Arellano Garcia, M.E., Carrasco-Legleu, C.E., De Leon-Fierro, L.G., Arenas-Berumen, E.A. [Factors affecting oxidative damage in obese children: an exploratory study]. Nutr Hosp. 2015;31(4):1499-503

Rosa, J.S., Oliver, S.R., Flores, R.L., Ngo, J., Milne, G.L., Zaldivar, F.P., et al. Altered inflammatory, oxidative, and metabolic responses to exercise in pediatric obesity and type 1 diabetes. Pediatr Diabetes. 2011;12(5):464-72

Sanchez, M., Panahi, S., Tremblay, A. Childhood obesity: a role for gut microbiota? Int J Environ Res Public Health. 2015;12(1):162-75

Tuomi, T., Santoro, N., Caprio, S., Cai, M., Weng, J., Groop, L. The many faces of diabetes: a disease with increasing heterogeneity. Lancet. 2014;383(9922):1084-94

Vaarala, O. Is the origin of type 1 diabetes in the gut? Immunol Cell Biol. 2012;90(3):271-6

Vaarala, O. Gut microbiota and type 1 diabetes. Rev Diabet Stud. 2012;9(4):251-9

Books:

Bolin, K., Cawley, J.H. The economics of obesity. 1st ed. Amsterdam; Boston: Elsevier JAI; 2007.

Oral/Dental Health

Breiner, Mark, DDS. Whole-Body Dentistry: A Complete Guide to Understanding the Impact of Dentistry on Total Health. 2011.

Price, Weston A., DDS. Nutrition and Physical Degeneration. 2009.

PANS/PANDAS

Baytunca, M.B. “[Evaluation of a Neuropsychiatric Disorder: From PANDAS to PANS and CANS].” Turk Psikiyatri Derg. 2016 Summer;27(2):0.

Braniste, V., et al. “The gut microbiota influences blood-brain barrier permeability in mice.Sci Transl Med. 2014 Nov 19;6(263):263ra158. doi: 10.1126/scitranslmed.3009759.

Brown, K., et al. “Pediatric Acute-Onset Neuropsychiatric Syndrome Response to Oral Corticosteroid Bursts: An Observational Study of Patients in an Academic Community-Based PANS Clinic.” J Child Adolesc Psychopharmacol. 2017 Jul 17. doi: 10.1089/cap.2016.0139. [Epub ahead of print]

Brown, K.D., et al. “Effect of Early and Prophylactic Nonsteroidal Anti-Inflammatory Drugs on Flare Duration in Pediatric Acute-Onset Neuropsychiatric Syndrome: An Observational Study of Patients Followed by an Academic Community-Based Pediatric Acute-Onset Neuropsychiatric Syndrome Clinic.” J Child Adolesc Psychopharmacol. 2017 Jul 11. doi: 10.1089/cap.2016.0193. [Epub ahead of print]

Calaprice, D., et al. “A Survey of Pediatric Acute-Onset Neuropsychiatric Syndrome Characteristics and Course.” J Child Adolesc Psychopharmacol. 2017 Jan 31. doi: 10.1089/cap.2016.0105. [Epub ahead of print]

Chang, K., et al. “Clinical evaluation of youth with pediatric acuteonset neuropsychiatric syndrome (PANS): recommendations from the 2013 PANS Consensus Conference.” J Child Adolesc Psychopharmacol. 2015 Feb;25(1):3-13. doi: 10.1089/cap.2014.0084. Epub 2014 Oct 17.

Chang, K., et al. “Special issue on pediatric acute-onset neuropsychiatric syndrome.J Child Adolesc Psychopharmacol. 2015 Feb;25(1):1-2. doi: 10.1089/cap.2015.2511.

Chiarello, F., et al. “An expert opinion on PANDAS/PANS: highlights and controversies.” Int J Psychiatry Clin Pract. 2017 Jun;21(2):91-98. doi: 10.1080/13651501.2017.1285941. Epub 2017 Feb 13.

Cooperstock, M., et al. “Clinical Management of Pediatric Acute-Onset Neuropsychiatric Syndrome: Part III—Treatment and Prevention of Infections” J Child Adolesc Psychopharmacol. 2017 Jul, ahead of print. doi.org/10.1089/cap.2016.0151

Cox, C.J., et al. “Antineuronal antibodies in a heterogeneous group of youth and young adults with tics and obsessive-compulsive disorder.J Child Adolesc Psychopharmacol. 2015 Feb;25(1):76-85. doi: 10.1089/cap.2014.0048. Epub 2015 Feb 6.

Dale, R.C. “Immune-mediated extrapyramidal movement disorders, including Sydenham chorea.Handb Clin Neurol. 2013;112:1235-41. doi: 10.1016/B978-0-444-52910-7.00046-5.

Dasdaq, S., et al. “Effects of 2.4 GHz radiofrequency radiation emitted from Wi-Fi equipment on microRNA expression in brain tissue.” Int J Radiat Biol. 2015 Jul;91(7):555-61. doi: 10.3109/09553002.2015.1028599. Epub 2015 May 20.

Ercan, T.E., et al. “Mycoplasma pneumoniae infection and obsessive-compulsive disease: a case report.J Child Neurol. 2008 Mar;23(3):338-40. Epub 2007 Dec 13.

Frankovich, J., et al. “Clinical Management of Pediatric Acute-Onset Neuropsychiatric Syndrome: Part II—Use of Immunomodulatory Therapies” J Child Adolesc Psychopharmacol. 2017 Jul, ahead of print. doi.org/10.1089/cap.2016.0148

Frankovich, J., et al. “Five youth with pediatric acute-onset neuropsychiatric syndrome of differing etiologies.J Child Adolesc Psychopharmacol. 2015 Feb;25(1):31-7. doi: 10.1089/cap.2014.0056.

Frankovich, J., et al. “Multidisciplinary clinic dedicated to treating youth with pediatric acute-onset neuropsychiatric syndrome: presenting characteristics of the first 47 consecutive patients.J Child Adolesc Psychopharmacol. 2015 Feb;25(1):38-47. doi: 10.1089/cap.2014.0081.

Gaughan, T., et al. “Rapid Eye Movement Sleep Abnormalities in Children with Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS).J Clin Sleep Med. 2016 Jul 15;12(7):1027-32. doi: 10.5664/jcsm.5942.

Gerardi, D.M., et al. “PANDAS and comorbid Kleine-Levin syndrome.J Child Adolesc Psychopharmacol. 2015 Feb;25(1):93-8. doi: 10.1089/cap.2014.0064. Epub 2014 Oct 20.

Hazlett, H.C., et al. “Early brain development in infants at high risk for autism spectrum disorder.” Nature, 542, 348–351 (16 Feb 2017).

Hirai, N., et al. “A new infectious encephalopathy syndrome, clinically mild encephalopathy associated with excitotoxicity (MEEX).J Neurol Sci. 2017 Feb 15;373:138-141. doi: 10.1016/j.jns.2016.12.043. Epub 2016 Dec 24.

Jaspers-Fayer, F., et al. “Prevalence of Acute-Onset Subtypes in Pediatric Obsessive-Compulsive Disorder.” J Child Adolesc Psychopharmacol. 2017 May;27(4):332-341. doi: 10.1089/cap.2016.0031. Epub 2017 Jan 25.

Jyonouchi, H., et al. “Cytokine profiles by peripheral blood monocytes are associated with changes in behavioral symptoms following immune insults in a subset of ASD subjects: an inflammatory subtype?J Neuroinflammation. 2014 Oct 27;11:187. doi: 10.1186/s12974-014-0187-2.

Kim, C., et al. “Strep and Urinary Frequency: Is There a Connection?” New England Section of the American Urological Association, 75th Annual Meeting. 2006 Sep 28-30.

Kovacevic, M., et al. “Use of Intravenous Immunoglobulin in the Treatment of Twelve Youths with Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections.J Child Adolesc Psychopharmacol. 2015 Feb;25(1):65-9. doi: 10.1089/cap.2014.0067. Epub 2015 Feb 6.

Lancaster, Eric. “The Diagnosis and Treatment of Autoimmune Encephalitis.J Clin Neurol. 2016 Jan;12(1):1-13. doi: 10.3988/jcn.2016.12.1.1.

Latimer, M.E., et al. “Therapeutic plasma apheresis as a treatment for 35 severely ill children and adolescents with pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections.J Child Adolesc Psychopharmacol. 2015 Feb;25(1):70-5. doi: 10.1089/cap.2014.0080. Epub 2015 Feb 6.

Mahony, T., et al. “Improvement of psychiatric symptoms in youth following resolution of sinusitis.Int J Pediatr Otorhinolaryngol. 2017 Jan;92:38-44. doi: 10.1016/j.ijporl.2016.10.034. Epub 2016 Oct 31.

Mahony, T., et al. “Palatal Petechiae in the Absence of Group A Streptococcus in Pediatric Patients with Acute-Onset Neuropsychiatric Deterioration: A Cohort Study.” J Child Adolesc Psychopharmacol. 2017 Apr 7. doi: 10.1089/cap.2016.0153. [Epub ahead of print]

Marcello, A., et al. “Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS): An Evolving Concept.Tremor Other Hyperkinet Mov (N Y). 2013 Sep 25;3. pii: tre-03-167-4158-7. doi: 10.7916/D8ZC81M1. eCollection 2013.

Mink, J., et al. “Acute postinfectious movement and psychiatric disorders in children and adolescents.J Child Neurol. 2011 Feb;26(2):214-7. doi: 10.1177/0883073810378534. Epub 2010 Nov 22.

Muir, K.E., et al. “A case report of obsessive-compulsive disorder following acute disseminated encephalomyelitis.Pediatrics. 2013 Sep;132(3):e771-4. doi: 10.1542/peds.2012-2876. Epub 2013 Aug 5.

Murphy, T.K., et al. “Cefdinir for recent-onset pediatric neuropsychiatric disorders: a pilot randomized trial.J Child Adolesc Psychopharmacol. 2015 Feb;25(1):57-64. doi: 10.1089/cap.2014.0010. Epub 2014 Oct 9.

Murphy, T.K., et al. “Characterization of the pediatric acute-onset neuropsychiatric syndrome phenotype.” J Child Adolesc Psychopharmacol. 2015 Feb;25(1):14-25. doi: 10.1089/cap.2014.0062. Epub 2014 Oct 14.

Murphy, T.K., et al. “A Double-Blind Randomized Placebo-Controlled Pilot Study of Azithromycin in Youth with Acute-Onset Obsessive-Compulsive Disorder.” J Child Adolesc Psychopharmacol. 2017 Mar 30. doi: 10.1089/cap.2016.0190. [Epub ahead of print]

Murphy, T.K., et al. “Pediatric acute-onset neuropsychiatric syndrome.Psychiatr Clin North Am. 2014 Sep;37(3):353-74. doi: 10.1016/j.psc.2014.06.001.

Nadeau, J.M., et al. “A pilot trial of cognitive-behavioral therapy augmentation of antibiotic treatment in youth with pediatric acute-onset neuropsychiatric syndrome-related obsessive-compulsive disorder.J Child Adolesc Psychopharmacol. 2015 May;25(4):337-43. doi: 10.1089/cap.2014.0149.

Orefici, G., et al. “Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS).Streptococcus pyogenes : Basic Biology to Clinical Manifestations [Internet]. Oklahoma City (OK): University of Oklahoma Health Sciences Center; 2016-. 2016 Feb 10.

Orlovska, S., et al. “Association of Streptococcal Throat Infection With Mental Disorders: Testing Key Aspects of the PANDAS Hypothesis in a Nationwide Study.” JAMA Psychiatry. 2017 Jul 1;74(7):740-746. doi: 10.1001/jamapsychiatry.2017.0995.

Parker-Athill, E.C., et al. “Cytokine correlations in youth with tic disorders.J Child Adolesc Psychopharmacol. 2015 Feb;25(1):86-92. doi: 10.1089/cap.2014.0103. Epub 2015 Feb 6.

Pearlman, D.M., et al. “Anti-basal ganglia antibodies in primary obsessive-compulsive disorder: systematic review and meta-analysis.Br J Psychiatry. 2014 Jul;205(1):8-16. doi: 10.1192/bjp.bp.113.137018.

Sahyouni, R., et al. “Effects of concussion on the blood–brain barrier in humans and rodents.” Journal of Concussion. 2017 Jan 1; 10.1177/2059700216684518

Spartz, E.J., et al. “Course of Neuropsychiatric Symptoms After Introduction and Removal of Nonsteroidal Anti-Inflammatory Drugs: A Pediatric Observational Study.” J Child Adolesc Psychopharmacol. 2017 Jul 11. doi: 10.1089/cap.2016.0179. [Epub ahead of print]

Swedo, S.E., et al. “Clinical Presentation of Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections in Research and Community Settings.J Child Adolesc Psychopharmacol. 2015 Feb;25(1):26-30. doi: 10.1089/cap.2014.0073.

Swedo, S.E., et al. “Overview of Treatment of Pediatric Acute-Onset Neuropsychiatric Syndrome.” J Child Adolesc Psychopharmacol. 2017 Jul 19. doi: 10.1089/cap.2017.0042. [Epub ahead of print]

Tang, J., et al. “Exposure to 900 MHz electromagnetic fields activates the mkp-1/ERK pathway and causes blood-brain barrier damage and cognitive impairment in rats.Brain Res. 2015 Mar 19;1601:92-101. doi: 10.1016/j.brainres.2015.01.019. Epub 2015 Jan 15.

Thienemann M. et al. “Clinical Management of Pediatric Acute-Onset Neuropsychiatric Syndrome: Part I-Psychiatric and Behavioral Interventions.” J Child Adolesc Psychopharmacol. 2017 Jul 19. doi: 10.1089/cap.2016.0145. [Epub ahead of print]

Tona, J.T., et al. “Impact of PANS and PANDAS Exacerbations on Occupational Performance: A Mixed-Methods Study.” Am J Occup Ther. 2017 May/Jun;71(3):7103220020P1-7103220020P9. doi: 10.5014/ajot.2017.022285.

Toufexis, M.D., et al. “Disordered eating and food restrictions in children with PANDAS/PANS.J Child Adolesc Psychopharmacol 2015 Feb;25(1):48-56. doi: 10.1089/cap.2014.0063. Epub 2014 Oct 20.

Vitaliti, G., et al. “A new clinical feature associated with familial early-onset of dystonic-guttural tics: An unusual diagnosis of PANDAS.J Pediatr Neurosci. 2014 Jan;9(1):79-81. doi: 10.4103/1817-1745.131497.

Wang, Hsiuying. “Anti-NMDA Receptor Encephalitis.Int J Mol Sci. 2017 Jan 18;18(1). pii: E193. doi: 10.3390/ijms18010193.

Retained Reflexes

Books:

Brandes, Bonnie. “The Symphony of Reflexes: Interventions for Human Development, Autism, ADHD, CP, and Other Neurological Disorders“. 2016

Goddard, Sally. “Reflexes, Learning And Behavior: A Window into the Child’s Mind : A Non-Invasive Approach to Solving Learning & Behavior Problems“. 2005

Sensory Processing Disorder

Aguilera, M., Cerda-Cuellar, M., Martinez, V. Antibiotic-induced dysbiosis alters host-bacterial interactions and leads to colonic sensory and motor changes in mice. Gut Microbes. 2015;6(1):10-23

Darling, A.L., et al. “Association between maternal vitamin D status in pregnancy and neurodevelopmental outcomes in childhood: results from the Avon Longitudinal Study of Parents and Children (ALSPAC).Br J Nutr 2017 Jun;117(12):1682-1692.

Books:

Biel, Lindsey. “Raising a Sensory Smart Child: The Definitive Handbook for Helping Your Child with Sensory Processing Issues.” Revised Edition, 2009

Hong, Maria Rickert. “Almost Autism: Recovering Children from Sensory Processing Disorder, A Reference for Parents and Practitioners.” 2014.

Kranowitz, Carol. “The Out-of-Sync Child: Recognizing and Coping with Sensory Processing Disorder.” Revised edition. 2006.

Skin Problems

da Costa Baptista, I.P., Accioly, E., de Carvalho Padilha, P. Effect of the use of probiotics in the treatment of children with atopic dermatitis; a literature review. Nutr Hosp. 2013;28(1):16-26

Drago, L., Toscano, M., De Vecchi, E., Piconi, S., Iemoli, E. Changing of fecal flora and clinical effect of L. salivarius LS01 in adults with atopic dermatitis. J Clin Gastroenterol. 2012;46 Suppl:S56-63

Eichenfield, L.F., Tom, W.L., Chamlin, S.L., Feldman, S.R., Hanifin, J.M., Simpson, E.L., et al. Guidelines of care for the management of atopic dermatitis: section 1. Diagnosis and assessment of atopic dermatitis. J Am Acad Dermatol. 2014;70(2):338-51

Oh, S.Y., Chung, J., Kim, M.K., Kwon, S.O., Cho, B.H. Antioxidant nutrient intakes and corresponding biomarkers associated with the risk of atopic dermatitis in young children. Eur J Clin Nutr. 2010;64(3):245-52

Orivuori, L., Mustonen, K., de Goffau, M.C., Hakala, S., Paasela, M., Roduit, C., et al. High level of fecal calprotectin at age 2 months as a marker of intestinal inflammation predicts atopic dermatitis and asthma by age 6. Clin Exp Allergy. 2015

Speech and Language Issues

Frye, R.E., et al. “Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial.Mol Psychiatry. 2018 Feb; 23(2): 247–256.

Thyroid Conditions

Watt, T., Hegedus, L., Bjorner, J.B., Groenvold, M., Bonnema, S.J., Rasmussen, A.K., et al. Is Thyroid Autoimmunity per se a Determinant of Quality of Life in Patients with Autoimmune Hypothyroidism? Eur Thyroid J. 2012;1(3):186-92

Urinary Tract Infection

Hinhumpatch, P., Navasumrit, P., Chaisatra, K., Promvijit, J., Mahidol, C., Ruchirawat, M. Oxidative DNA damage and repair in children exposed to low levels of arsenic in utero and during early childhood: application of salivary and urinary biomarkers. Toxicol Appl Pharmacol. 2013;273(3):569-79.