What Is Autism Spectrum Disorder?

Autism Spectrum DisorderAutism spectrum disorder is a developmental disorder characterized by impairments in sensory, language, social-emotional and behavior areas.

It is a “spectrum disorder,” with manifestations ranging from mild to severe.

What Your Doctor Will Tell You About Autism

Traditional practitioners believe that autism is a mystery.

They will say that, “We have little knowledge of possible causes, and that treatments should address impairments in the processing of touch, movement, audition and vision, speech, language, and behavior.

Accompanying physical issues such as allergies, breathing problems, gastrointestinal issues, and others are unrelated to the diagnosis.”

Another Way to Think About Autism

Autism spectrum disorder is a multi-system developmental disorder caused by an accumulation of environmental stressors turning on a genetically susceptible predisposition to the condition.

Just like a bridge that collapses when a heavily laden truck crosses it, the body collapses into autism as the multiple triggers add up.

Depending upon the triggers, different systems are affected in each individual, related to his/her bioindividuality.

Rebalancing the body, and bringing it back to health, requires removing the possible triggers from the external and internal environment, and adding necessary nutrients through food and supplementation.

Autism Checklist to Start

  • Begin with lifestyle basics: sufficient sleep and toxin-free air, food and water.
  • Remove all possible toxins from the home in detergents, soaps, lotions and personal care products.
  • Identify and treat other possible underlying food and environmental allergies and sensitivities.
  • Support the body and the immune system with basic nutrients like vitamin D, essential fatty acids and phytonutrients.

If You’ve Addressed These Issues and Are Still Looking for Help

  • Have your child screened for services from the local public school, even if your child does not attend. The law mandates that you are entitled to free services from birth.
  • Ask your doctor to run basic blood, urine, and stool tests for baselines on function. Be sure and include a test for vitamin D, which is not routine.
  • Take all processed foods out of your child’s diet. Consider removing all sugars, flours (especially wheat), and dairy products, as well.
  • Look into diets and therapies that heal the gut and restore microbial balance and diversity in your child’s gastrointestinal system
  • Seek out a local support group for families of children with special needs.

Visit the Epidemic Answers Provider Directory to find a practitioner near you.

Resources:

Autism, Depression and Alzheimer’s: Is There a Connection?

AutoImmunity and Autism

Birth Trauma: A Common Cause for Developmental Delays

Disordered Metal Metabolism in Autism Spectrum Disorders

The Immune System and Autism

Mitochondria and Autism

Parasites and Autism: Why Some Kids don’t Recover

Playing with Young Children with Autism Spectrum Disorders

Safety issues in Autism

Total Load Theory

Vision and Autism

Vitamin D and Autism: Is There a Connection?

Yeast Metabolites and Distractibility

Adams JB, Audhya T, McDonough-Means S, Rubin RA, Quig D, Geis E, et al. Effect of a vitamin/mineral supplement on children and adults with autism. BMC Pediatr. 2011;11:111  http://www.ncbi.nlm.nih.gov/pubmed/22151477

Alabdali A, Al-Ayadhi L, El-Ansary A. A key role for an impaired detoxification mechanism in the etiology and severity of autism spectrum disorders. Behav Brain Funct. 2014;10:14  http://www.ncbi.nlm.nih.gov/pubmed/24776096

Alabdali A, Al-Ayadhi L, El-Ansary A. Association of social and cognitive impairment and biomarkers in autism spectrum disorders. J Neuroinflammation. 2014;11:4   http://www.ncbi.nlm.nih.gov/pubmed/24400970

Barrett B. Substantial lifelong cost of autism spectrum disorder. J Pediatr. 2014;165(5):1068-9   http://www.ncbi.nlm.nih.gov/pubmed/25441393

Bateman C. Autism–mitigating a global epidemic. S Afr Med J. 2013;103(5):276-7  http://www.ncbi.nlm.nih.gov/pubmed/23971108

Bitsika V, Sharpley CF, Andronicos NM, Agnew LL. Hypothalamus-pituitary-adrenal axis daily fluctuation, anxiety and age interact to predict cortisol concentrations in boys with an autism spectrum disorder. Physiol Behav. 2015;138:200-7 http://www.ncbi.nlm.nih.gov/pubmed/25446203

Bouder JN, Spielman S, Mandell DS. Brief report: Quantifying the impact of autism coverage on private insurance premiums. J Autism Dev Disord. 2009;39(6):953-7  http://www.ncbi.nlm.nih.gov/pubmed/19214727

Bradstreet JJ, Smith S, Baral M, Rossignol DA. Biomarker-guided interventions of clinically relevant conditions associated with autism spectrum disorders and attention deficit hyperactivity disorder. Altern Med Rev. 2010;15(1):15-32 http://www.ncbi.nlm.nih.gov/pubmed/20359266

Brown CM, Austin DW, Busija L. Observable essential fatty acid deficiency markers and autism spectrum disorder. Breastfeed Rev. 2014;22(2):21-6  http://www.ncbi.nlm.nih.gov/pubmed/25109097

Buescher AV, Cidav Z, Knapp M, Mandell DS. Costs of autism spectrum disorders in the United Kingdom and the United States. JAMA Pediatr. 2014;168(8):721-8 http://www.ncbi.nlm.nih.gov/pubmed/24911948

Bull G, Shattock P, Whiteley P, Anderson R, Groundwater PW, Lough JW, et al. Indolyl-3-acryloylglycine (IAG) is a putative diagnostic urinary marker for autism spectrum disorders. Med Sci Monit. 2003;9(10):CR422-5 http://www.ncbi.nlm.nih.gov/pubmed/14523330

Critchfield JW, van Hemert S, Ash M, Mulder L, Ashwood P. The potential role of probiotics in the management of childhood autism spectrum disorders. Gastroenterol Res Pract. 2011;2011:161358 http://www.ncbi.nlm.nih.gov/pubmed/22114588

Cubala-Kucharska M. The review of most frequently occurring medical disorders related to aetiology of autism and the methods of treatment. Acta Neurobiol Exp (Wars). 2010;70(2):141-6 http://www.ncbi.nlm.nih.gov/pubmed/20628438

Dave D, Fernandez JM, National Bureau of Economic Research. The effect of an increase in autism prevalence on the demand for auxiliary healthcare workers : evidence from California. Cambridge, MA: National Bureau of Economic Research; 2012. 37 p. p.  http://www.nber.org/papers/w18238

de Magistris L, Familiari V, Pascotto A, Sapone A, Frolli A, Iardino P, et al. Alterations of the intestinal barrier in patients with autism spectrum disorders and in their first-degree relatives. J Pediatr Gastroenterol Nutr. 2010;51(4):418-24 http://www.ncbi.nlm.nih.gov/pubmed/20683204

Deth R, Muratore C, Benzecry J, Power-Charnitsky VA, Waly M. How environmental and genetic factors combine to cause autism: A redox/methylation hypothesis. Neurotoxicology. 2008;29(1):190-201 http://www.ncbi.nlm.nih.gov/pubmed/18031821

Elamin NE, Al-Ayadhi LY. Brain autoantibodies in autism spectrum disorder. Biomark Med. 2014;8(3):345-52 http://www.ncbi.nlm.nih.gov/pubmed/24712424

El-Ansary A, Al-Ayadhi L. Neuroinflammation in autism spectrum disorders. J Neuroinflammation. 2012;9:265. http://www.ncbi.nlm.nih.gov/pubmed/23170784

El-Ansary A, Al-Ayadhi L. Lipid mediators in plasma of autism spectrum disorders. Lipids Health Dis. 2012;11:160. http://www.ncbi.nlm.nih.gov/pubmed/23170784

Faber S, Zinn GM, Boggess A, Fahrenholz T, Kern JC 2nd, Kingston HM. A cleanroom sleeping environment’s impact on markers of oxidative stress, immune dysregulation, and behavior in children with autism spectrum disorders. BMC Complement Altern Med. 2015;15:71  http://www.ncbi.nlm.nih.gov/pubmed/25887094

Frustaci A, Neri M, Cesario A, Adams JB, Domenici E, Dalla Bernardina B, et al. Oxidative stress-related biomarkers in autism: systematic review and meta-analyses. Free Radic Biol Med. 2012;52(10):2128-41 http://www.ncbi.nlm.nih.gov/pubmed/22542447

Frye RE, Delatorre R, Taylor H, Slattery J, Melnyk S, Chowdhury N, et al. Redox metabolism abnormalities in autistic children associated with  mitochondrial disease. Transl Psychiatry. 2013;3:e273  http://www.ncbi.nlm.nih.gov/pubmed/23778583

Frye RE, James SJ. Metabolic pathology of autism in relation to redox metabolism. Biomark Med. 2014;8(3):321-30 http://www.ncbi.nlm.nih.gov/pubmed/24712422

Gabriele S, Sacco R, Persico AM. Blood serotonin levels in autism spectrum disorder: a systematic review and meta-analysis. Eur Neuropsychopharmacol. 2014;24(6):919-29  http://www.ncbi.nlm.nih.gov/pubmed/24613076

Gadow KD, Roohi J, DeVincent CJ, Kirsch S, Hatchwell E. Association of COMT (Val158Met) and BDNF (Val66Met) gene polymorphisms with anxiety, ADHD and tics in children with autism spectrum disorder. J Autism Dev Disord. 2009;39(11):1542-51 http://www.ncbi.nlm.nih.gov/pubmed/19582565

Gadow KD, Devincent CJ, Olvet DM, Pisarevskaya V, Hatchwell E. Association of DRD4 polymorphism with severity of oppositional defiant disorder, separation anxiety disorder and repetitive behaviors in children with autism spectrum disorder. Eur J Neurosci. 2010;32(6):1058-65  http://www.ncbi.nlm.nih.gov/pubmed/20731709

Gebril OH, Meguid NA. HFE gene polymorphisms and the risk for autism in Egyptian children and impact on the effect of oxidative stress. Dis Markers. 2011;31(5):289-94  http://www.ncbi.nlm.nih.gov/pubmed/22048270

Geier DA, Kern JK, Geier MR. The biological basis of autism spectrum disorders: Understanding causation and treatment by clinical geneticists. Acta Neurobiol Exp (Wars). 2010;70(2):209-26  http://www.ncbi.nlm.nih.gov/pubmed/20628444

Ghanizadeh A. Increased glutamate and homocysteine and decreased glutamine levels in autism: a review and strategies for future studies of amino acids in autism. Dis Markers. 2013;35(5):281-6  http://www.ncbi.nlm.nih.gov/pubmed/24167375

Goldani AA, Downs SR, Widjaja F, Lawton B, Hendren RL. Biomarkers in autism. Front Psychiatry. 2014;5:100 http://www.ncbi.nlm.nih.gov/pubmed/25161627

Guyol G. Who’s crazy here?: Steps for recovery without drugs for: ADD/ADHD, addiction & eating disorders, anxiety & PTSD, depression, bipolar disorder, schizophrenia, autism. 1st U.S. ed. Stonington, CT: Ajoite Pub.; 2010. 123 p. P.  http://www.crazyrecovery.com/

Herbert MR, Russo JP, Yang S, Roohi J, Blaxill M, Kahler SG, et al. Autism and environmental genomics. Neurotoxicology. 2006;27(5):671-84  http://www.ncbi.nlm.nih.gov/pubmed/16644012

Heyer NJ, Echeverria D, Woods JS. Disordered porphyrin metabolism: a potential biological marker for autism risk assessment. Autism Res. 2012;5(2):84-92  http://www.ncbi.nlm.nih.gov/pubmed/16644012

James SJ, Cutler P, Melnyk S, Jernigan S, Janak L, Gaylor DW, et al. Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism. Am J Clin Nutr. 2004;80(6):1611-7  http://www.ncbi.nlm.nih.gov/pubmed/15585776

Jyonouchi H, Geng L, Ruby A, Zimmerman-Bier B. Dysregulated innate immune responses in young children with autism spectrum disorders: their relationship to gastrointestinal symptoms and dietary intervention. Neuropsychobiology. 2005;51(2):77-85 http://www.ncbi.nlm.nih.gov/pubmed/12378124.

Kaluzna-Czaplinska J, Zurawicz E, Struck W, Markuszewski M. Identification of organic acids as potential biomarkers in the urine of autistic children using gas chromatography/mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2014;966:70-6 http://www.ncbi.nlm.nih.gov/pubmed/24565890

Kaufman RK. Autism breakthrough: the groundbreaking method that has helped families all over the world. First edition. ed. New York: St. Martin’s Press; 2014. x, 353 pages p  http://www.autismbreakthrough.com/

Kern JK, Geier DA, Adams JB, Geier MR. A biomarker of mercury body-burden correlated with diagnostic domain specific clinical symptoms of autism spectrum disorder. Biometals. 2010;23(6):1043-51 http://www.ncbi.nlm.nih.gov/pubmed/20532957

Kuwabara H, Yamasue H, Koike S, Inoue H, Kawakubo Y, Kuroda M, et al. Altered metabolites in the plasma of autism spectrum disorder: a capillary electrophoresis time-of-flight mass spectroscopy study. PLoS One. 2013;8(9):e73814 http://www.ncbi.nlm.nih.gov/pubmed/24058493

Lavelle TA, Weinstein MC, Newhouse JP, Munir K, Kuhlthau KA, Prosser LA. Economic burden of childhood autism spectrum disorders. Pediatrics. 2014;133(3):e520-9  http://www.ncbi.nlm.nih.gov/pubmed/24515505

Li SO, Wang JL, Bjorklund G, Zhao WN, Yin CH. Serum copper and zinc levels in individuals with autism spectrum disorders. Neuroreport. 2014;25(15):1216-20  https://documentinghope.com/therapeutics-treatment-approaches/

Maher P. Methylglyoxal, advanced glycation end products and autism: is there a connection? Med Hypotheses. 2012;78(4):548-52 http://www.ncbi.nlm.nih.gov/pubmed/22325990

Momeni N, Bergquist J, Brudin L, Behnia F, Sivberg B, Joghataei MT, et al. A novel bloodbased biomarker for detection of autism spectrum disorders. Transl Psychiatry. 2012;2:e91  http://www.ncbi.nlm.nih.gov/pubmed/22832856

Nankova BB, Agarwal R, MacFabe DF, La Gamma EF. Enteric bacterial metabolites propionic and butyric acid modulate gene expression, including CREB-dependent catecholaminergic neurotransmission, in PC12 cells–possible relevance to autism spectrum disorders. PLoS One. 2014;9(8):e103740  http://www.ncbi.nlm.nih.gov/pubmed/25170769

Ngounou Wetie AG, Wormwood K, Thome J, Dudley E, Taurines R, Gerlach M, et al. A pilot proteomic study of protein markers in autism spectrum disorder. Electrophoresis. 2014;35(14):2046-54 http://www.ncbi.nlm.nih.gov/pubmed/24687421

Noto A, Fanos V, Barberini L, Grapov D, Fattuoni C, Zaffanello M, et al. The urinary metabolomics profile of an Italian autistic children population and their unaffected siblings. J Matern Fetal Neonatal Med. 2014;27 Suppl 2:46-52 http://www.ncbi.nlm.nih.gov/pubmed/25284177

Patrick RP, Ames BN. Vitamin D hormone regulates serotonin synthesis. Part 1: relevance for autism. FASEB J. 2014;28(6):2398-413 http://www.ncbi.nlm.nih.gov/pubmed/24558199

Peterson BS, Goh S, Dong Z. Brain lactate as a potential biomarker for comorbid anxiety disorder in autism spectrum disorder-reply. JAMA Psychiatry. 2015;72(2):190-1  http://www.ncbi.nlm.nih.gov/pubmed/25650815

Ranjbar A, Rashedi V, Rezaei M. Comparison of urinary oxidative biomarkers in Iranian children with autism. Res Dev Disabil. 2014;35(11):2751-5 http://www.ncbi.nlm.nih.gov/pubmed/25086736

Ratajczak HV. Theoretical aspects of autism: biomarkers–a review. J Immunotoxicol. 2011;8(1):80-94 http://www.ncbi.nlm.nih.gov/pubmed/21299356

Reynolds A, Krebs NF, Stewart PA, Austin H, Johnson SL, Withrow N, et al. Iron status in children with autism spectrum disorder. Pediatrics. 2012;130 Suppl 2:S154-9  http://www.ncbi.nlm.nih.gov/pubmed/23118246

Rutter M. Changing concepts and findings on autism. J Autism Dev Disord. 2013;43(8):1749-57 http://www.ncbi.nlm.nih.gov/pubmed/23359217

Ruggeri B, Sarkans U, Schumann G, Persico AM. Biomarkers in autism spectrum disorder: the old and the new. Psychopharmacology (Berl). 2014;231(6):1201-16  http://www.ncbi.nlm.nih.gov/pubmed/23359217

Spilioti M, Evangeliou AE, Tramma D, Theodoridou Z, Metaxas S, Michailidi E, et al. Evidence for treatable inborn errors of metabolism in a cohort of 187 Greek patients with autism spectrum disorder (ASD). Front Hum Neurosci. 2013;7:858 http://www.ncbi.nlm.nih.gov/pubmed/24399946

Theoharides TC. Is a subtype of autism an allergy of the brain? Clin Ther. 2013; 35(5):584-91 http://www.ncbi.nlm.nih.gov/pubmed/23688533

Thomas RH, Meeking MM, Mepham JR, Tichenoff L, Possmayer F, Liu S, et al. The enteric bacterial metabolite propionic acid alters brain and plasma phospholipid molecular species: further development of a rodent model of autism spectrum disorders. J Neuroinflammation. 2012;9:153 http://www.ncbi.nlm.nih.gov/pubmed/22747852

Wang L, Conlon MA, Christophersen CT, Sorich MJ, Angley MT. Gastrointestinal microbiota and metabolite biomarkers in children with autism spectrum disorders. Biomark Med. 2014;8(3):331-44 http://www.ncbi.nlm.nih.gov/pubmed/24712423

Woodman AC, Smith LE, Greenberg JS, Mailick MR. Change in autism symptoms and maladaptive behaviors in adolescence and adulthood: the role of positive family processes. J Autism Dev Disord. 2015;45(1):111-26 http://www.ncbi.nlm.nih.gov/pubmed/25070471

BOOKS

Romaniec M. Victory over autism: lessons on raising an autism-free child. New York, NY: Skyhorse Publishing; 2015. pages cm p http://www.amazon.com/Victory-over-Autism-Practical-Recovery/dp/1634505158

Sears RW. The autism book: what every parent needs to know about early detection, treatment, recovery, and prevention. 1st ed. New York, NY: Little, Brown; 2010. xv, 398 p.p  http://www.askdrsears.com/topics/health-concerns/vaccines/dr-bobs-definitive-guide-autism-book

Bock, Kenneth. Healing the New Childhood Epidemics: Autism, ADHD, Asthma, and Allergies: The Groundbreaking Program for the 4-A Disorders. New York, NY. Ballantine Books, 2008 https://www.amazon.com/Healing-New-Childhood-Epidemics-Groundbreaking/dp/0345494512

Brandes, Bonnie. The Symphony of Reflexes: Interventions for Human Development, Autism, ADHD, CP, and Other Neurological Disorders. 2016 https://www.amazon.com/Symphony-Reflexes-Interventions-Development-Neurological/dp/150285502

Campbell-McBride, Natasha.  Gut and Psychology Syndrome: Natural Treatment for Autism, Dyspraxia, A.D.D., Dyslexia, A.D.H.D., Depression, Schizophrenia.  2010 https://www.amazon.com/Psychology-Syndrome-D-D-D-H-D-Schizophrenia/dp/0954852028

Giustra-Kozek J. Healing without hurting: treating ADHD, apraxia, and autism spectrum disorders naturally and effectively without harmful medication. Howard Beach, NY: Changing Lives Press; 2014. xiii, 370 p. p. https://www.amazon.com/Healing-without-Hurting-Effectively-Medications/dp/0989452980

Herbert MR, Weintraub K. The Autism Revolution: whole-body strategies for making life all it can be. New York: Ballantine Books; 2012https://www.amazon.com/Autism-Revolution-Whole-Body-Strategies-Making/dp/0345527208

Lemer PS. Outsmarting Autism: The Ultimate Guide to Management, Healing and Prevention for Individuals with Autism Spectrum Disorders, Tarentum, PA, Word Association Publishers, 2014 https://www.amazon.com/Outsmarting-Autism-Patricia-Lemer/dp/1595719709

Seroussi K. Unraveling the mystery of Autism and pervasive developmental disorder : a mother’s story of research and recovery. New York: Simon & Schuster; 2000. 288 p. p. https://www.amazon.com/Unraveling-Mystery-Pervasive-Developmental-Disorder/dp/0767907981